My understanding is that if you pured for a right handed golfer then the pure mark goes in the club at the 12 o’clock position.  So my question is would it make any difference if the puring mark went in the 6 o’clock position?  Asking because my fitter did this on my sim driver.  He says it doesn’t matter, and if I rotate the shaft 180 degrees it changes the lie angle from 54 to 60.

Answered question

Puring finds the most stable plane, regardless of the spine and flo oscillations.
Just because the POP is at a certain point, it doesn’t mean it extends through the shaft 180 degrees.
The puring folks SST Pure, specify puring for right or left handed golfers.